Equine infectious diseases pose ongoing challenges to performance, welfare, and stable management, making prevention and early intervention central to veterinary practice. This section examines the latest research and field protocols for identifying, treating, and controlling equine infections—from respiratory pathogens such as equine influenza (EIV) and equine herpesvirus (EHV-1/EHV-4) to bacterial threats like Lyme disease, strangles, and other parasites. You’ll find expert guidance on outbreak management, biosecurity planning, and disinfection strategies, along with updates on vector control and quarantine best practices. Articles in this hub explore evidence-based antimicrobial stewardship, interpretation of diagnostic tools like PCR and serum amyloid A testing, and case management techniques such as regional limb perfusion for localized infections. Coverage also extends to wound care and gut microbiome protection during antibiotic use. Explore the articles below for practical approaches to surveillance, treatment selection, and communication strategies that strengthen herd immunity and keep barns safer year-round. When it comes to preventing postoperative infections, a recent study shows less is more. Veterinarians can limit the course of prophylactic antibiotics… Nasal swabs may not be everyone’s idea of a good time, but Bettina Wagner, DVM, PhD, and her colleagues are more than… The antibiotic cephalothin appears to be kinder to the gut microbiome than other first-line antimicrobial agents, researchers in Japan have found, suggesting… Respiratory pathogens such as equine influenza (EIV) and equine herpesvirus (EHV‑1/EHV‑4), and bacterial diseases like strangles are frequent concerns. Lyme disease, EPM, tetanus, rabies, and proliferative enteropathy also occur and require targeted prevention and response plans. Implement written biosecurity protocols, quarantine new arrivals, and enforce strict hygiene and disinfection of shared equipment. Align vaccination schedules with AAEP guidance and establish temperature monitoring during outbreaks to detect cases early. PCR panels, serology, and acute‑phase markers such as Serum Amyloid A help identify infection stage and severity. Sampling method, timing, and test selection should be guided by clinical signs and epidemiologic context. Unnecessary or prolonged antibiotic use selects for resistant organisms, complicating future treatment. Culture and sensitivity testing, narrow‑spectrum choices, and avoidance of blanket prophylaxis are pillars of antimicrobial stewardship. Isolate the horse immediately, restrict movement on and off the property, and monitor temperatures of all contacts twice daily. Follow AAEP and regulatory guidance for quarantine duration, testing, and communication with neighboring facilities. Yes. Salmonella, MRSA, rabies, and certain leptospira strains pose risks to humans. Proper PPE, vaccination where applicable, and rigorous hygiene practices minimize exposure in clinics and barns. Improvements in molecular diagnostics, vaccine antigen design, and microbiome‑immune interactions are informing better prevention. Ongoing surveillance and data sharing refine outbreak response and biosecurity strategies worldwide.Infectious Diseases

Experts warn ‘Super’ El Niño could bring surge in mosquito-borne equine infections
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Preventing post-op infections: Stick to the short course



What topics presented during the 2025 AAEP Infectious Disease Track stood out?
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Avast, Ye Swabs! Mucosal Testing May Help Streamline Response to EHV Infection

Spike Protein Mutations Can Fuel Outbreaks of Western Equine Encephalitis
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What is the New World Screwworm and What Should We Communicate to Horse Owners?
Read articleFrequently Asked Infectious Disease Questions
What are the most common infectious diseases in horses?
How can barns prevent the spread of infectious disease?
Which diagnostic tests are most useful for detecting infection?
How does antimicrobial overuse drive resistance in horses?
What should I do if a horse tests positive for EHV?
Are any equine diseases zoonotic?
What research is advancing equine infectious disease control?
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